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Mutations That Rescue the Paralysis of Caenorhabditis elegans ric-8 (Synembryn) Mutants Activate the Gα(s) Pathway and Define a Third Major Branch of the Synaptic Signaling Network
To identify hypothesized missing components of the synaptic Gα(o)-Gα(q) signaling network, which tightly regulates neurotransmitter release, we undertook two large forward genetic screens in the model organism C. elegans and focused first on mutations that strongly rescue the paralysis of ric-8(md30...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Genetics Society of America
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449092/ https://ncbi.nlm.nih.gov/pubmed/15489510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032334 |
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