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Mutations That Rescue the Paralysis of Caenorhabditis elegans ric-8 (Synembryn) Mutants Activate the Gα(s) Pathway and Define a Third Major Branch of the Synaptic Signaling Network

To identify hypothesized missing components of the synaptic Gα(o)-Gα(q) signaling network, which tightly regulates neurotransmitter release, we undertook two large forward genetic screens in the model organism C. elegans and focused first on mutations that strongly rescue the paralysis of ric-8(md30...

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Detalhes bibliográficos
Main Authors: Schade, Michael A., Reynolds, Nicole K., Dollins, Claudia M., Miller, Kenneth G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449092/
https://ncbi.nlm.nih.gov/pubmed/15489510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032334
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