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Mutation Rate and Predicted Phenotypic Target Sizes in Ethylnitrosourea-Treated Mice

Chemical mutagenesis of the mouse is ongoing in several centers around the world, with varying estimates of mutation rate and number of sites mutable to phenotype. To address these questions, we sequenced ∼9.6 Mb of DNA from G(1) progeny of ethylnitrosourea-treated mice in a large, broad-spectrum sc...

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Detalles Bibliográficos
Main Authors: Concepcion, Dorothy, Seburn, Kevin L, Wen, Gen, Frankel, Wayne N, Hamilton, Bruce A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448829/
https://ncbi.nlm.nih.gov/pubmed/15514066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.029843
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