A Complex Interaction of Imprinted and Maternal-Effect Genes Modifies Sex Determination in Odd Sex (Ods) Mice

The transgenic insertional mouse mutation Odd Sex (Ods) represents a model for the long-range regulation of Sox9. The mutation causes complete female-to-male sex reversal by inducing a male-specific expression pattern of Sox9 in XX Ods/+ embryonic gonads. We previously described an A/J strain-specif...

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Main Authors: Poirier, Christophe, Qin, Yangjun, Adams, Carolyn P., Anaya, Yanett, Singer, Jonathan B., Hill, Annie E., Lander, Eric S., Nadeau, Joseph H., Bishop, Colin E.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2004
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448764/
https://ncbi.nlm.nih.gov/pubmed/15579706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032177
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