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Spontaneous Mutations in Diploid Saccharomyces cerevisiae: More Beneficial Than Expected

We performed a 1012-generation mutation-accumulation (MA) experiment in the yeast, Saccharomyces cerevisiae. The MA lines exhibited a significant reduction in mean fitness and a significant increase in variance in fitness. We found that 5.75% of the fitness-altering mutations accumulated were benefi...

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Bibliographic Details
Main Authors: Joseph, Sarah B., Hall, David W.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448740/
https://ncbi.nlm.nih.gov/pubmed/15611159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033761
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