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Role of the Unfolded Protein Response Pathway in Secretory Stress and Regulation of INO1 Expression in Saccharomyces cerevisiae

The unfolded protein response pathway (UPR) enables the cell to cope with the buildup of unfolded proteins in the endoplasmic reticulum (ER). UPR loss-of-function mutants, hac1Δ and ire1Δ, are also inositol auxotrophs, a phenotype associated with defects in expression of INO1, the most highly regula...

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Detalhes bibliográficos
Main Authors: Chang, Hak J., Jesch, Stephen A., Gaspar, Maria L., Henry, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448725/
https://ncbi.nlm.nih.gov/pubmed/15371354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032961
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