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The Drosophila U1-70K Protein Is Required for Viability, but Its Arginine-Rich Domain Is Dispensable

The conserved spliceosomal U1-70K protein is thought to play a key role in RNA splicing by linking the U1 snRNP particle to regulatory RNA-binding proteins. Although these protein interactions are mediated by repeating units rich in arginines and serines (RS domains) in vitro, tests of this domain&#...

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Detalhes bibliográficos
Main Authors: Salz, Helen K., Mancebo, Ricardo S. Y., Nagengast, Alexis A., Speck, Olga, Psotka, Mitchell, Mount, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448718/
https://ncbi.nlm.nih.gov/pubmed/15611175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032532
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