Microevolution of the Direct Repeat Locus of Mycobacterium tuberculosis in a Strain Prevalent in San Francisco

We describe a microevolutionary event of a prevalent strain of Mycobacterium tuberculosis that caused two outbreaks in San Francisco. During the second outbreak, a direct variable repeat was lost. We discuss the mechanisms of this change and the implications of analyzing multiple genetic loci in thi...

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Detalhes bibliográficos
Main Authors: Aga, Roxanne S., Fair, Elizabeth, Abernethy, Neil F., DeRiemer, Kathryn, Paz, E. Antonio, Kawamura, L. Masae, Small, Peter M., Kato-Maeda, Midori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448666/
https://ncbi.nlm.nih.gov/pubmed/16597893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.44.4.1558-1560.2006
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