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Positive and Negative Regulation of the Innate Antiviral Response and Beta Interferon Gene Expression by Deacetylation

Beta interferon (IFN-β) gene expression in response to virus infection relies on the dynamic assembly of a multiprotein enhanceosome complex that is initiated by the activation of two inducible transcription factors, interferon regulatory factor 3 (IRF3) and NF-κB. Virus or double-stranded RNA-induc...

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Detalhes bibliográficos
Main Authors: Nusinzon, Inna, Horvath, Curt M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446935/
https://ncbi.nlm.nih.gov/pubmed/16581785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.8.3106-3113.2006
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