NF-κB Regulates Spatial Memory Formation and Synaptic Plasticity through Protein Kinase A/CREB Signaling

Synaptic activity-dependent de novo gene transcription is crucial for long-lasting neuronal plasticity and long-term memory. In a forebrain neuronal conditional NF-κB-deficient mouse model, we demonstrate here that the transcription factor NF-κB regulates spatial memory formation, synaptic transmiss...

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Auteurs principaux: Kaltschmidt, Barbara, Ndiaye, Delphine, Korte, Martin, Pothion, Stéphanie, Arbibe, Laurence, Prüllage, Maria, Pfeiffer, Julia, Lindecke, Antje, Staiger, Volker, Israël, Alain, Kaltschmidt, Christian, Mémet, Sylvie
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446931/
https://ncbi.nlm.nih.gov/pubmed/16581769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.8.2936-2946.2006
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