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Catabolism of human IgG in mice sensitized to various IgG fragments. Similarities to the catabolism of rheumatoid IgG in mice.
Whole body elimination studies of human serum IgG have showm that C57Bl miceare tolerant to this protein at low concentrations. The present study demonstrates that tolerance to this protein may be broken by presensitization of the mouse with the pepsin-derived fragments of human IgG (F(ab)2 and pFc)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1975
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1445824/ https://ncbi.nlm.nih.gov/pubmed/1150312 |
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