Formation in the presence of C3 nephritic factor (C3NeF) of an alternative pathway C3 convertase containing uncleaved B.

C3 nephritic factor (C3NeF) interacts with native C3 and B in the absence of D to generate a C3 convertase containing an uncleaved form of B. Dose response studies with C3NeF and B, respectively, revealed incremental C3 inactivation without loss of B. These findings are in agreement with the previou...

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Bibliographic Details
Main Authors: Daha, M R, Fearon, D T, Austen, K F
Format: Artigo
Language:Inglês
Published: 1976
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1445153/
https://ncbi.nlm.nih.gov/pubmed/992711
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