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Stereoselective Hydrolysis of Pyrethroid-like Fluorescent Substrates by Human and Other Mammalian Liver Carboxylesterases

Mammalian hepatic carboxylesterases (CEs) play important roles in the detoxification of ester-containing pyrethroids, which are widely used for the control of agricultural pests and disease vectors such as mosquitoes. Pyrethroids and pyrethroid-like fluorescent substrates exhibit a consistent patter...

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Detalhes bibliográficos
Main Authors: Huang, Huazhang, Fleming, Christopher D., Nishi, Kosuke, Redinbo, Matthew R., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444893/
https://ncbi.nlm.nih.gov/pubmed/16167828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050072+
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