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Monensin Improves the Effectiveness of meso-Dimercaptosuccinate when Used to Treat Lead Intoxication in Rats

Among divalent cations, the ionophore monensin shows high activity and selectivity for the transport of lead ions (Pb(2+)) across phospholipid membranes. When coadministered to rats that were receiving meso-dimercaptosuccinate for treatment of Pb intoxication, monensin significantly increased the am...

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Autors principals: Hamidinia, Shawn A., Erdahl, Warren L., Chapman, Clifford J., Steinbaugh, Gregory E., Taylor, Richard W., Pfeiffer, Douglas R.
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440769/
https://ncbi.nlm.nih.gov/pubmed/16581534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.8279
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