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Orientation of a β-Hairpin Antimicrobial Peptide in Lipid Bilayers from Two-Dimensional Dipolar Chemical-Shift Correlation NMR

The orientation of a β-sheet membrane peptide in lipid bilayers is determined, for the first time, using two-dimensional (2D) (15)N solid-state NMR. Retrocyclin-2 is a disulfide-stabilized cyclic β-hairpin peptide with antibacterial and antiviral activities. We used 2D separated local field spectros...

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Bibliographische Detailangaben
Hauptverfasser: Tang, Ming, Waring, Alan J., Lehrer, Robert I., Hong, Mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440742/
https://ncbi.nlm.nih.gov/pubmed/16500957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062075
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