Influence of N-Linked Glycosylation of Porcine Reproductive and Respiratory Syndrome Virus GP5 on Virus Infectivity, Antigenicity, and Ability To Induce Neutralizing Antibodies

Porcine reproductive and respiratory syndrome virus (PRRSV) glycoprotein 5 (GP5) is the most abundant envelope glycoprotein and a major inducer of neutralizing antibodies in vivo. Three putative N-linked glycosylation sites (N34, N44, and N51) are located on the GP5 ectodomain, where a major neutral...

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Bibliographische Detailangaben
Hauptverfasser: Ansari, Israrul H., Kwon, Byungjoon, Osorio, Fernando A., Pattnaik, Asit K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440468/
https://ncbi.nlm.nih.gov/pubmed/16571816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3994-4004.2006
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