Hepatitis B Surface Antigen Vector Delivers Protective Cytotoxic T-Lymphocyte Responses to Disease-Relevant Foreign Epitopes

Although hepatitis B surface antigen (HBsAg) per se is highly immunogenic, its use as a vector for the delivery of foreign cytotoxic T-lymphocyte (CTL) epitopes has met with little success because of constraints on HBsAg stability and secretion imposed by the insertion of foreign sequence into criti...

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Detalles Bibliográficos
Main Authors: Woo, Wai-Ping, Doan, Tracy, Herd, Karen A., Netter, Hans-Jürgen, Tindle, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440427/
https://ncbi.nlm.nih.gov/pubmed/16571814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3975-3984.2006
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