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The Peptide-Binding and ATPase Domains of Recombinant hsc70 Are Required To Interact with Rotavirus and Reduce Its Infectivity

The heat shock cognate protein hsc70 has been implicated as a postattachment cell receptor for rotaviruses. Here we show that hsc70 interacts specifically with rotaviruses through its peptide-binding domain, since a recombinant full-length hsc70 protein and its peptide-binding domain, but not its AT...

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Detalhes bibliográficos
Main Authors: Pérez-Vargas, Jimena, Romero, Pedro, López, Susana, Arias, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440403/
https://ncbi.nlm.nih.gov/pubmed/16537599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3322-3331.2006
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