Astrocytes Survive Chronic Infection and Cytopathic Effects of the ts1 Mutant of the Retrovirus Moloney Murine Leukemia Virus by Upregulation of Antioxidant Defenses

The ts1 mutant of Moloney murine leukemia virus (MoMuLV) induces a neurodegenerative disease in mice, in which glial cells are infected by the retrovirus but neurons are not. ts1 infection of primary astrocytes, or of the immortalized astrocytic cell line C1, results in accumulation of the ts1 gPr80...

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Autors principals: Qiang, Wenan, Kuang, Xianghong, Liu, Jinrong, Liu, Na, Scofield, Virginia L., Reid, Amy J., Jiang, Yuhong, Stoica, Gheorghe, Lynn, William S., Wong, Paul K. Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440401/
https://ncbi.nlm.nih.gov/pubmed/16537594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3273-3284.2006
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