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Enhanced Local Symmetry Interactions Globally Stabilize a Mutant Virus Capsid That Maintains Infectivity and Capsid Dynamics

Structural transitions in viral capsids play a critical role in the virus life cycle, including assembly, disassembly, and release of the packaged nucleic acid. Cowpea chlorotic mottle virus (CCMV) undergoes a well-studied reversible structural expansion in vitro in which the capsid expands by 10%....

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Hlavní autoři: Speir, Jeffrey A., Bothner, Brian, Qu, Chunxu, Willits, Deborah A., Young, Mark J., Johnson, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440388/
https://ncbi.nlm.nih.gov/pubmed/16537626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3582-3591.2006
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