Acetylated Tat Regulates Human Immunodeficiency Virus Type 1 Splicing through Its Interaction with the Splicing Regulator p32

The human immunodeficiency virus type 1 (HIV-1) potent transactivator Tat protein mediates pleiotropic effects on various cell functions. Posttranslational modification of Tat affects its activity during viral transcription. Tat binds to TAR and subsequently becomes acetylated on lysine residues by...

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Главные авторы: Berro, Reem, Kehn, Kylene, de la Fuente, Cynthia, Pumfery, Anne, Adair, Richard, Wade, John, Colberg-Poley, Anamaris M., Hiscott, John, Kashanchi, Fatah
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2006
Предметы:
Genome Replication and Regulation of Viral Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440361/
https://ncbi.nlm.nih.gov/pubmed/16537587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3189-3204.2006
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