Acetylated Tat Regulates Human Immunodeficiency Virus Type 1 Splicing through Its Interaction with the Splicing Regulator p32

The human immunodeficiency virus type 1 (HIV-1) potent transactivator Tat protein mediates pleiotropic effects on various cell functions. Posttranslational modification of Tat affects its activity during viral transcription. Tat binds to TAR and subsequently becomes acetylated on lysine residues by...

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Autors principals: Berro, Reem, Kehn, Kylene, de la Fuente, Cynthia, Pumfery, Anne, Adair, Richard, Wade, John, Colberg-Poley, Anamaris M., Hiscott, John, Kashanchi, Fatah
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2006
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440361/
https://ncbi.nlm.nih.gov/pubmed/16537587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3189-3204.2006
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