Acetylated Tat Regulates Human Immunodeficiency Virus Type 1 Splicing through Its Interaction with the Splicing Regulator p32

The human immunodeficiency virus type 1 (HIV-1) potent transactivator Tat protein mediates pleiotropic effects on various cell functions. Posttranslational modification of Tat affects its activity during viral transcription. Tat binds to TAR and subsequently becomes acetylated on lysine residues by...

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Autori principali: Berro, Reem, Kehn, Kylene, de la Fuente, Cynthia, Pumfery, Anne, Adair, Richard, Wade, John, Colberg-Poley, Anamaris M., Hiscott, John, Kashanchi, Fatah
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2006
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440361/
https://ncbi.nlm.nih.gov/pubmed/16537587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3189-3204.2006
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