Acetylated Tat Regulates Human Immunodeficiency Virus Type 1 Splicing through Its Interaction with the Splicing Regulator p32

The human immunodeficiency virus type 1 (HIV-1) potent transactivator Tat protein mediates pleiotropic effects on various cell functions. Posttranslational modification of Tat affects its activity during viral transcription. Tat binds to TAR and subsequently becomes acetylated on lysine residues by...

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Main Authors: Berro, Reem, Kehn, Kylene, de la Fuente, Cynthia, Pumfery, Anne, Adair, Richard, Wade, John, Colberg-Poley, Anamaris M., Hiscott, John, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440361/
https://ncbi.nlm.nih.gov/pubmed/16537587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3189-3204.2006
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