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Cloning and Expression Analysis of the pcbAB-pcbC β-Lactam Genes in the Marine Fungus Kallichroma tethys

Here we report the identification of the β-lactam biosynthesis genes pcbAB and pcbC from a cosmid genomic DNA library of the marine fungus Kallichroma tethys. A BLAST homology search showed that they share high sequence identity with the δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine (ACV) synthetases and...

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Udgivet i:Appl Environ Microbiol
Principais autores: Kim, Chi-fai, Lee, Simon K. Y., Price, Jackie, Jack, Ralph W., Turner, Geoffrey, Kong, Richard Y. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12571064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.2.1308-1314.2003
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