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Computer simulation of chaperone effects of Archaeal C/D box sRNA binding on rRNA folding

Archaeal C/D box small RNAs (sRNAs) are homologues of eukaryotic C/D box small nucleolar RNAs (snoRNAs). Their main function is guiding 2′-O-ribose methylation of nucleotides in rRNAs. The methylation requires the pairing of an sRNA antisense element to an rRNA target site with formation of an RNA–R...

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Autori principali: Schoemaker, Ruud J. W., Gultyaev, Alexander P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435978/
https://ncbi.nlm.nih.gov/pubmed/16614451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl154
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