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Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study

BACKGROUND: The way various antiretroviral drugs and drug combinations affect HIV-1 infection in the central nervous system is still largely unknown. The aim of this study was to determine the cerebrospinal fluid (CSF) steady-state concentrations of saquinavir and nelfinavir in relation to plasma co...

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Main Authors: Yilmaz, Aylin, Fuchs, Dietmar, Hagberg, Lars, Nillroth, Ulrika, Ståhle, Lars, Svensson, Jan-Olof, Gisslén, Magnus
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435910/
https://ncbi.nlm.nih.gov/pubmed/16566834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-6-63
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