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Demyelination as a test for a mobile Na channel modulator in frog node of Ranvier.

We found previously that the external surface of frog skeletal muscle fibers can be irreversibly modified by treatment with the amino group-specific reagent, trinitrobenzene sulfonic acid (TNBS). Reaction of the muscle membrane with TNBS permanently shifts the potential dependence of the sodium chan...

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Autors principals: Pappone, P A, Cahalan, M D
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435148/
https://ncbi.nlm.nih.gov/pubmed/2579686
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