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High intracellular pH reversibly prevents gating-charge immobilization in squid axons.

Squid giant axons were used to study the reversible effects of high intracellular pH (pHi) on gating currents. Under depolarization, when Na channels are activated, internal solutions buffered at high pHi (10.2) affect considerably the time course of gating charge associated with channel closing, QO...

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Bibliografiske detaljer
Main Authors: Wanke, E, Testa, P L, Prestipino, G, Carbone, E
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434832/
https://ncbi.nlm.nih.gov/pubmed/6652218
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