Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer

BACKGROUND: Chemotherapy for pancreatic carcinoma often has severe side effects that limit its efficacy. The glucocorticoid (GC) dexamethasone (DEX) is frequently used as co-treatment to prevent side effects of chemotherapy such as nausea, for palliative purposes and to treat allergic reactions. Whi...

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Główni autorzy: Zhang, Chengwen, Kolb, Armin, Büchler, Peter, Cato, Andrew CB, Mattern, Jürgen, Rittgen, Werner, Edler, Lutz, Debatin, Klaus-Michael, Büchler, Markus W, Friess, Helmut, Herr, Ingrid
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2006
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434760/
https://ncbi.nlm.nih.gov/pubmed/16539710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-61
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