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Mucosal polyamine profile in normal and adapting (hypo and hyperplastic) intestine: effects of DFMO treatment.

The polyamines, putrescine, spermidine, and spermine, are believed to play an important role in modulating normal and adaptive intestinal mucosal growth. Polyamine synthesis is rate limited by ornithine decarboxylase (ODC) and ODC activity is specifically inhibited by -difluoromethyl ornithine (DFMO...

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Détails bibliographiques
Auteurs principaux: Hosomi, M, Lirussi, F, Stace, N H, Vaja, S, Murphy, G M, Dowling, R H
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434572/
https://ncbi.nlm.nih.gov/pubmed/3121452
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