Antiviral Activity of Shiga Toxin Requires Enzymatic Activity and Is Associated with Increased Permeability of the Target Cells

This study expanded our earlier finding that Shiga toxin type 1 (Stx1) has activity against bovine leukemia virus (BLV) (W. A. Ferens and C. J. Hovde, Infect. Immun. 68:4462-4469, 2000). The Stx molecular motifs required for antiviral activity were identified, and a mechanism of Stx action on virall...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Basu, Indira, Ferens, Witold A., Stone, Diana M., Hovde, Carolyn J.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.327-334.2003
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