Differential Expression of Gamma Interferon mRNA Induced by Attenuated and Virulent Mycobacterium tuberculosis in Guinea Pig Cells after Mycobacterium bovis BCG Vaccination

To determine whether Mycobacterium bovis BCG vaccination would alter gamma interferon (IFN-γ) mRNA expression in guinea pig cells exposed to Mycobacterium tuberculosis, we cloned a cDNA encoding guinea pig IFN-γ from a spleen cell cDNA library. The cDNA is composed of 1,110 bp, with an open reading...

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Bibliographic Details
Main Authors: Jeevan, Amminikutty, Yoshimura, Teizo, Lee, Kyeong Eun, McMurray, David N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC143318/
https://ncbi.nlm.nih.gov/pubmed/12496185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.354-364.2003
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