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Cytotoxic Effects of Streptolysin O and Streptolysin S Enhance the Virulence of Poorly Encapsulated Group A Streptococci

Although the toxicity of streptolysin O (SLO) and streptolysin S (SLS) in purified group A streptococci (GAS) has been established, the effect of these molecules in natural infection is not well understood. To identify whether biologically relevant concentrations of SLO and SLS were cytotoxic to epi...

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Detalhes bibliográficos
Main Authors: Sierig, Gabriele, Cywes, Colette, Wessels, Michael R., Ashbaugh, Cameron D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC143243/
https://ncbi.nlm.nih.gov/pubmed/12496195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.446-455.2003
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