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A GRA1 DNA Vaccine Primes Cytolytic CD8(+) T Cells To Control Acute Toxoplasma gondii Infection

Protective immunity against Toxoplasma gondii is known to be mediated mainly by T lymphocytes and gamma interferon (IFN-γ). The contribution of CD4(+) and CD8(+) T-lymphocyte subsets to protective immune responses against T. gondii infection, triggered by a GRA1 (p24) DNA vaccine, was assessed in th...

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Published in:Infect Immun
Main Authors: Scorza, T., D'Souza, S., Laloup, M., Dewit, J., De Braekeleer, J., Verschueren, H., Vercammen, M., Huygen, K., Jongert, E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143232/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.309-316.2003
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