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Domain-Induced Activation of Human Phospholipase A(2) Type IIA: Local versus Global Lipid Composition
Secretory human phospholipase A(2) type IIA (PLA(2)-IIA) catalyzes the hydrolysis of the sn-2 ester bond in glycerolipids to produce fatty acids and lysolipids. The enzyme is coupled to the inflammatory response, and its specificity toward anionic membrane interfaces suggests a role as a bactericida...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Biophysical Society
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1432114/ https://ncbi.nlm.nih.gov/pubmed/16461407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070987 |
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