Gas Phase Characterization of the Noncovalent Quaternary Structure of Cholera Toxin and the Cholera Toxin B Subunit Pentamer

Cholera toxin (CTx) is an AB(5) cytotonic protein that has medical relevance in cholera and as a novel mucosal adjuvant. Here, we report an analysis of the noncovalent homopentameric complex of CTx B chain (CTx B(5)) using electrospray ionization triple quadrupole mass spectrometry and tandem mass s...

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Detalhes bibliográficos
Main Authors: Williams, Jonathan P., Smith, Daniel C., Green, Brian N., Marsden, Brian D., Jennings, Keith R., Roberts, Lynne M., Scrivens, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1432099/
https://ncbi.nlm.nih.gov/pubmed/16461395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076455
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