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Protein protein interactions, evolutionary rate, abundance and age

BACKGROUND: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biological premise that a highly interacting protein will be more restricted in its sequence changes. However, to date severa...

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Bibliographic Details
Main Authors: Saeed, Ramazan, Deane, Charlotte M
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1431566/
https://ncbi.nlm.nih.gov/pubmed/16533385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-128
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