Genetic Alteration of Capsule Type but Not PspA Type Affects Accessibility of Surface-Bound Complement and Surface Antigens of Streptococcus pneumoniae

The Streptococcus pneumoniae capsular polysaccharides and pneumococcal surface protein A (PspA) are major determinants of virulence that are antigenically variable and capable of eliciting protective immune responses. By genetically switching the pspA genes of the capsule type 2 strain D39 and the c...

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Vydáno v:	Infect Immun
Hlavní autoři:	Abeyta, Melanie, Hardy, Gail G., Yother, Janet
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Molecular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143148/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.218-225.2003
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