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Tauroursodeoxycholic Acid Prevents Amyloid-β Peptide–Induced Neuronal Death Via a Phosphatidylinositol 3-Kinase–Dependent Signaling Pathway

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Amyloid-β (Aβ) peptide has been implicated in the pathogenesis of Alzheimer’s disease, where a significant loss of neuronal cells is thought to occur by apoptosis. In this...

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Bibliografski detalji
Glavni autori: Solá, Susana, Castro, Rui E, Laires, Pedro A, Steer, Clifford J, Rodrigues, Cecília MP
Format: Artigo
Jezik:Inglês
Izdano: ScholarOne 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430980/
https://ncbi.nlm.nih.gov/pubmed/15208744
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