A Plasminogen Activator Inhibitor-1 Promoter Polymorphism and Idiopathic Interstitial Pneumonia

The normal fibrinolytic activity within the alveolar space is suppressed in fibrotic lung diseases in part because of increased levels of plasminogen activator inhibitor-1 (PAI-1). Studies with animals have shown that inhibition of the plasminogen system by PAI-1 increases the generation of pulmonar...

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Hlavní autoři: Kim, Kevin K, Flaherty, Kevin R., Long, Qi, Hattori, Noboru, Sisson, Thomas H., Colby, Thomas V, Travis, William D, Martinez, Fernando J, Murray, Susan, Simon, Richard H
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430380/
https://ncbi.nlm.nih.gov/pubmed/12765340
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