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“Viral déjà vu” elicits organ-specific immune disease independent of reactivity to self

Autoimmune diseases are often precipitated by viral infections. Yet our current understanding fails to explain how viruses trigger organ-specific autoimmunity despite thymic tolerance extending to many nonlymphohematopoietic self antigens. Additionally, a key epidemiological finding needs to be expl...

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Detalhes bibliográficos
Main Authors: Merkler, Doron, Horvath, Edit, Bruck, Wolfgang, Zinkernagel, Rolf M., del la Torre, Juan Carlos, Pinschewer, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430358/
https://ncbi.nlm.nih.gov/pubmed/16604192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27372
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