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The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells

We have used a novel conditional transgenic system to study the mechanisms of angioproliferation induced by viral G protein–coupled receptor (vGPCR), the constitutively active chemokine receptor encoded by human herpesvirus 8 (HHV8, also known as Kaposi sarcoma herpesvirus). Using this system, we we...

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Autori principali: Grisotto, Marcos G., Garin, Alexandre, Martin, Andrea P., Jensen, Kristian K., Chan, PokMan, Sealfon, Stuart C., Lira, Sergio A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430356/
https://ncbi.nlm.nih.gov/pubmed/16604194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26666
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