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CARM1 Regulates Proliferation of PC12 Cells by Methylating HuD

HuD is an RNA-binding protein that has been shown to induce neuronal differentiation by stabilizing labile mRNAs carrying AU-rich instability elements. Here, we show a novel mechanism of arginine methylation of HuD by coactivator-associated arginine methyltransferase 1 (CARM1) that affected mRNA tur...

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Detalhes bibliográficos
Main Authors: Fujiwara, Tatsuji, Mori, Yasutake, Chu, Dong Ling, Koyama, Yoshihisa, Miyata, Shingo, Tanaka, Hiroyuki, Yachi, Kohji, Kubo, Tateki, Yoshikawa, Hideki, Tohyama, Masaya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430293/
https://ncbi.nlm.nih.gov/pubmed/16508003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2273-2285.2006
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