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Murine Cathepsin F Deficiency Causes Neuronal Lipofuscinosis and Late-Onset Neurological Disease
Cathepsin F (cat F) is a widely expressed lysosomal cysteine protease whose in vivo role is unknown. To address this issue, mice deficient in cat F were generated via homologous recombination. Although cat F(−/−) mice appeared healthy and reproduced normally, they developed progressive hind leg weak...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430281/ https://ncbi.nlm.nih.gov/pubmed/16508006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2309-2316.2006 |
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