Lipid Raft Targeting of Hematopoietic Protein Tyrosine Phosphatase by Protein Kinase C θ-Mediated Phosphorylation

Protein kinase C θ (PKC θ) is unique among PKC isozymes in its translocation to the center of the immune synapse in T cells and its unique downstream signaling. Here we show that the hematopoietic protein tyrosine phosphatase (HePTP) also accumulates in the immune synapse in a PKC θ-dependent manner...

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Autori principali: Nika, Konstantina, Charvet, Céline, Williams, Scott, Tautz, Lutz, Bruckner, Shane, Rahmouni, Souad, Bottini, Nunzio, Schoenberger, Stephen P., Baier, Gottfried, Altman, Amnon, Mustelin, Tomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430257/
https://ncbi.nlm.nih.gov/pubmed/16479000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1806-1816.2006
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