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Induction of delta-aminolaevulinic acid synthase in leucocytes of patients on phenytoin therapy--comparison with changes in rat hepatic tissue.
1 In rats daily phenytoin (DPH) administration resulted in an increase in hepatic cytochrome P450 content. The rise in cytochrome P450 was associated with a temporary increase in the acitvity of hepatic delta-aminolaevulinic acid (ALA) synthase. 2 In patients newly commenced on DPH anticonvulsant th...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1980
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1429979/ https://ncbi.nlm.nih.gov/pubmed/7378249 |
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