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Roles of hepatic blood flow and enzyme activity in the kinetics of propranolol and sotalol.

1 The roles of the hepatic blood flow and the drug oxidizing enzyme system in eliminating oral propranolol and sotalol were studied in twelve subjects with biopsy proven liver parenchymal disease. 2 The apparent plasma clearance of propranolol was closely related both to the in vivo (antipyrine test...

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Detalhes bibliográficos
Main Authors: Pirttiaho, H I, Sotaniemi, E A, Pelkonen, R O, Pitkänen, U, Anttila, M, Sundqvist, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429970/
https://ncbi.nlm.nih.gov/pubmed/7378257
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