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Modification of phenytoin clearance by valproic acid in normal subjects.

1 The effect of valproic acid on the distribution and elimination kinetics of intravenously administered phenytoin has been investigated in eight normal volunteers. 2 In each of the subjects studied the volume of distribution of phenytoin increased significantly during treatment with sodium valproat...

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Detalhes bibliográficos
Main Authors: Frigo, G M, Lecchini, S, Gatti, G, Perucca, E, Crema, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429910/
https://ncbi.nlm.nih.gov/pubmed/391257
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