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Desensitization of the beta-adrenoceptor of lymphocytes from normal subjects and asthmatic patients in vitro.

1 A lymphocyte culture method has been developed for studying in vitro the effect of prolonged exposure (24 h) to isoprenaline (10(-8) to 10(-6) mol/l) and prostaglandin E1 (PGE1; 2.8 x 10(-6) mol/l). 2 The cyclic AMP response to isoprenaline is reduced by prolonged exposure to isoprenaline. The deg...

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Main Authors: Greenacre, J K, Schofield, P, Conolly, M E
格式: Artigo
語言:Inglês
出版: 1978
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429258/
https://ncbi.nlm.nih.gov/pubmed/207294
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