On the Mechanism of Gene Amplification Induced under Stress in Escherichia coli

Gene amplification is a collection of processes whereby a DNA segment is reiterated to multiple copies per genome. It is important in carcinogenesis and resistance to chemotherapeutic agents, and can underlie adaptive evolution via increased expression of an amplified gene, evolution of new gene fun...

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Bibliographic Details
Main Authors: Slack, Andrew, Thornton, P. C, Magner, Daniel B, Rosenberg, Susan M, Hastings, P. J
Format: Artigo
Language:Inglês
Published: Public Library of Science 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428787/
https://ncbi.nlm.nih.gov/pubmed/16604155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020048
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