On the Mechanism of Gene Amplification Induced under Stress in Escherichia coli

Gene amplification is a collection of processes whereby a DNA segment is reiterated to multiple copies per genome. It is important in carcinogenesis and resistance to chemotherapeutic agents, and can underlie adaptive evolution via increased expression of an amplified gene, evolution of new gene fun...

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Autores principales: Slack, Andrew, Thornton, P. C, Magner, Daniel B, Rosenberg, Susan M, Hastings, P. J
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428787/
https://ncbi.nlm.nih.gov/pubmed/16604155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020048
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